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Each refill and week of opioid prescription is associated with a large increase in opioid misuse among opioid naive patients Postsurgical prescriptions for opioid naive patients and association with overdose and misuse The data from this study suggest that duration of the prescription rather than dosage is more strongly associated with ultimate misuse in the early postsurgical period.

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Surgeons struggle with adequately treating their patients’ pain needs while being mindful of the risks of opioids. It quantifies the disconnect between provider perception and patient consumption by simultaneously surveying outlier prescribers and the consumption patterns of patients overprescribed opioids. This study examines the principal determinants of opioid overprescribing